—In this study we performed comprehensive
biological and morphological analysis of dermis-derived stem
cells and compared them with bone marrow- and adipose
tissue-derived stem cells. According to obtained results we can
emphasize that analyzed somatic stem cells shared
morphological features, expression of surface antigens as well
as growth kinetics, but differ in chondrogenic potential.
Skin-derived stem cells have an inferior potential for
chondrogenic differentiation. So this fact decreases their
potential for cartilage tissue engineering.
—Biological characteristics, chondrogenic
differentiation, morphology, somatic stem cells.
M. Bohac, and J. Fedeles are with the Department of Plastic,
Reconstructive and Aesthetic Surgery, Faculty of Medicine, Comenius
University, Pažítkova 4, 82101 Bratislava, Slovakia (e-mail:
S. Polak, and J. Rusnakova are with the Institute of Histology and
Embryology, Faculty of Medicine, Comenius University, Sasinkova 4,
81108 Bratislava, Slovakia (e-mail: firstname.lastname@example.org).
Z. Varchulova Novakova and L. Danisovic are with the Institute of
Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine,
Comenius University, Sasinkova 4, 81108 Bratislava, Slovakia (e-mail:
Cite:M. Bohac, S. Polak, J. Fedels, Z. Varchulova Novakova, J. Rusnakova, and L. Danisovic, "Do Dermis-Derived Stem Cells Have the Same Characteristics as Bone Marrow- and Adipose Tissue-Derived Stem Cells?," International Journal of Bioscience, Biochemistry and Bioinformatics vol. 3, no. 6, pp. 630-634, 2013.